Development of Novel & Efficient Cap Analogs & Ionizable Lipids for mRNA Based Vaccines & Therapeutics
Time: 11:45 am
day: Day 1 Track 1 AM
Details:
Novel trinucloside AG and AU cap analogs amenable to synthesizing mRNAs and saRNAs with an enhanced protein expression profile
- One-pot synthesis of fluorescently labeled mRNA for real-time in vitro and in vivo tracking, and mRNA delivery system screening
- Efficient and fast degrading ionizable lipid for mRNA LNP delivery
- Application of LZCaps in mRNA vaccines and protein replacement therapies