Overcoming dsRNA Challenge: Innovation in Assays and Enzymes
Time: 1:00 pm
day: Day 2 Track 2 PM
Details:
- Current status of mRNA therapeutic drugs:dsRNA can strongly stimulate the intracellular RNA receptors RIG-I and MDA5, activate the innate immune response, and cause inflammation. Therefore, the content of dsRNA is related to the safety and efficacy of vaccines
- mRNA therapeutic drug process development challenges and solutions:It will describe the dsRNA quantitative detection and process control challenges encountered during development, and propose solutions to overcome these challenges
- Vazyme's work in mRNA raw materials and process innovation: GMP Grade, DMF Record
