Thomas Langenickel
Chief Medical Officer Ethris
Dr. Langenickel is Chief Medical Officer at Ethris. Prior to his current role, Dr. Langenickel gained two decades of pharmaceutical industry experience in drug discovery, translational medicine and clinical drug development including regulatory submissions in respiratory, cardiovascular, and metabolic diseases, resulting in three marketed medicines for the treatment of heart failure and asthma. Dr. Langenickel obtained his M.D. and Ph.D. from the Humboldt University of Berlin, Germany, trained in Clinical Pharmacology and Internal Medicine/Cardiology at the Max-Delbrück Center for Molecular Medicine and the Charité in Berlin, Germany, and completed a post-doctoral fellowship in vascular biology at the National Heart, Lung, and Blood Institute, NIH, USA.
Seminars
- Explore how Ethris is developing ETH47, a first-in-class mRNA-based nasal spray treatment for uncontrolled asthma, using their proprietary SNIM®RNA and SNaP LNP® technology platforms
- Discuss how ETH47 encodes interferon lambda (IFNλ), aiming to boost innate immune defense in the airways and address viral triggers of asthma exacerbations, with Phase 1 trials showing good safety and target engagement
- Discover how a Phase 2 clinical trial is underway to evaluate ETH47’s effectiveness in reducing asthma symptoms after a rhinovirus challenge in adults with asthma