Allison August

Allison August

Company: Moderna

Job title: VP, Clinical Development, Infectious Diseases

Seminars:

Lipid-Encapsulated mRNA Delivery of a Monoclonal Antibody with Neutralizing Activity Against Chikungunya Virus: Results From a Phase 1 Trial 2:15 pm

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day: Day One

Panel Discussion 5:00 pm

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day: Day One

Lipid-Encapsulated mRNA Delivery of a Monoclonal Antibody with Neutralizing Activity Against Chikungunya Virus: Results From a Phase 1 Trial 2:15 pm

This phase 1, first-in-human, randomized, placebo-controlled, proof-ofconcept trial conducted from January 2019 to June 2020 evaluated the safety and pharmacology of mRNA-1944, a lipid nanoparticle-encapsulated messenger RNA encoding the heavy and light chains of a CHIKV-specific monoclonal neutralizing antibody, CHKV-24 (NCT03829384) The primary outcome was to evaluate the safety and tolerability of escalating doses of…Read more

day: Day One

Panel Discussion 5:00 pm

With mRNA- based vaccines now established for certain infectious diseases, it is now important to realise the opportunities of such mRNA- based vaccine therapeutic applications and the surrounding regulatory requirements. From development to commercialization, we will explore aspects of mRNA- based vaccines beyond Sars-COVID-19. What does the future look like for the next generation of…Read more

day: Day One

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