Nose-to-brain Delivery of Oligonucleotides
Time: 4:30 pm
day: Focus Day
Details:
- Showcasing the delivery to the brain remains an incredibly challenging but holds immense promise for nucleic acids
- Evaluating the state-of-the-art for oligonucleotide therapies to the CNS is highly invasive direct delivery (e.g.., intrathecal injection directly into the cerebrospinal fluid)
- Describing work using formulations and a localization device to deliver oligonucleotides as in a minimally-invasive way into the brain via the nose-to-brain route