Nose-to-brain Delivery of Oligonucleotides

Time: 4:30 pm
day: Focus Day


  • Showcasing the delivery to the brain remains an incredibly challenging but holds immense promise for nucleic acids
  • Evaluating the state-of-the-art for oligonucleotide therapies to the CNS is highly invasive direct delivery (e.g.., intrathecal injection directly into the cerebrospinal fluid)
  • Describing work using formulations and a localization device to deliver oligonucleotides as in a minimally-invasive way into the brain via the nose-to-brain route